These two cases demonstrate that extra-abdominal node metastasis may rarely occur in GIST, either initially or in the setting of widespread disease. In selected cases with confirmed or suspected lymph node metastases, lymph node dissection should be considered. Metachronous extra-abdominal lymph node metastasis represents a late event in high-risk GISTs and cannot be controlled by drug therapy alone.
次は2013年の日本発のリポートです。 The association of VEGF-C expression with tumor lymphatic vessel density and lymph node metastasis in patients with gastric cancer and gastrointestinal stromal tumor. 胃癌およびGISTの患者におけるVEGF-C発現と腫瘍リンパ管密度およびリンパ節転移との関連 https://europepmc.org/article/med/23574654