これ完全にGIST患者の特殊ケースですね。これらにもう無関係の76歳の男性です。 全然知らないのでImatinib and premature ovarian failureと検索をしました。そして出てきたのですが、そのサイト参照がきません。でもコピペし翻訳をしました。
原文は: Some females who receive cancer treatment have premature ovarian failure (POF), also called premature menopause. The term “premature ovarian failure” describes a stop in normal ovarian functions in a woman younger than 40 years. Unlike menopause, this is not a natural occurrence. When POF is caused by cancer treatment, it is unlikely that a girl or woman will have subsequent menstrual periods or have the ability to become pregnant naturally. Generally, POF is managed with hormone replacement therapy, including estrogen and progesterone and sometimes also testosterone. Girls and women with POF are encouraged to eat a healthy diet and exercise regularly (aerobics and weight training) to decrease the health risks of osteoporosis and heart disease. Supplements or medications for bone health may be prescribed. At this point, there is no treatment to restore fertility for someone diagnosed with POF. Medications can be prescribed to assist with managing POF and regulating hormones.